刘雳宇

简介：

1980年生于成都。2004年毕业于中国科学技术大学力学与机械工程系，获学士学位；2008年获香港科技大学纳米科学与纳米技术博士学位；之后在美国普林斯顿大学物理系工作，历任博士后研究员，讲师等职务。2012年加入中国科学院物理研究所“百人计划”，任特聘研究员，博士生导师。2015年0638太阳集团教授。

现为：

国家级青年人才

国家“973”青年项目首席科学家

国家级人才联谊会副秘书长

重庆市青年领军人才协会副理事长

重庆市欧美同学会副会长

重庆市政协常委

中国科学院“卢嘉锡”人才奖，东京工业大学青年科学家奖，重庆市十佳科技青年奖，重庆市物理学科带头人

实验室主页：http://bmphys.cqu.edu.cn/index.htm

研究方向：

1. 癌症生物物理：基于改变肿瘤微环境的癌症治疗新方法探索；

2. 微流控类器官芯片的研究与应用；

3. 自组织机器人集群，自组织集群行为涌现机理研究。

基金项目：

1. 科技部“973计划”青年科学家专题（2013CB837200）

“三维微纳米生物芯片在肝癌和大肠癌肝转移中的分子机理研究及其临床应用”

2. 自然科学基金面上项目(11604030）

“功能性弹性血管的动力学及在重大疾病研究中的应用”

3. 自然科学基金面上项目(11474345)

“3-D生物芯片中癌细胞侵袭组织的集体行为和动力学研究“

4. 北京市自然科学基金（7154221）

“数字影像分析结合3-D打印技术探索心血管FFR的体外无创诊断”

5. 自然科学基金面上项目（11974066）

“介观尺度下癌细胞侵袭取向性胶原纤维的动力学研究”

代表性论文：

1. Gao W., Trung V. P., Shengkai L., Michael W., Junle Q., Yan P., Guo C., Daniel I. G., Simon A. L., Robert H. A., L.Liu, "Emergent Field-Driven Robot Swarm States", Physical Review Letters 126,108002 (2021)

2. Qihui F., Yu Z., Xiaochen W., Ruipei X.,Yu D., Boyi W., Xiaoyu Y., Ying L., L. Liu, Yunliang L., Ming L., Yuanjin Z., Yang J., Fangfu Y, "Dynamically re‐organized collagen fiber bundles transmit mechanical signals and induce strongly correlated cell migration and self‐organization", Angew. Chem. Int. Ed. DOI:https://doi.org/10.1002/anie.202016084 (2021)

3. Y. Lv, G. Li, H. Peng, Y. Liu, J. Yao, G. Wang, J. Sun, J. Liu, H. Zhang, G. Chen, L. Liu,"Development of elastic artificial vessels with a digital pulse flow      system to investigate the risk of restenosis and vasospasm", Lab on a Chip 20(16):3051-3059(2020)

4. J. Sun, L. Zhang, L. Cui, X. Luo, G. He,X. Dong, L. He, J. Zhang,J. Sun, G. Chen, Y. Lv, L. Liu,"Gestational age estimation from ultrasound fetal biometrics in China", Clin. Exp. Obstet. Gynecol  47(5): 714-722(2020)

5. J. Zheng, Y. Cheng, Y. Huang, S.Wang, L. Liu,G. Chen, "Drop impacting on a surface with adjustable wettability based on the dielectrowetting effect", Phys.      Fluids 32, 097108 (2020)

6. G. Chen, J. Zheng, L. Liu, L.Xu, "Application of Microfluidics in Wearable Devices", Small Methods 1900688 (2019)

7. Y. He, L. Xiong, X. Gao, M. Hai, Y. Liu,G. Wang, G. Chen, J. Shuai, Y. Jiao, X. Zhang, R. Liu, L. Liu,"Morphological quantification of proliferation-to-invasion transition in tumor spheroids", BBA - General Subjects 1864(2019)129460

8. Y. Zheng, H. Nan, Y. Liu, Q. Fan, X.Wang, R. Liu, L. Liu, "Modeling cell migration regulated by cell extracellular-matrix micromechanical coupling", Physical      Review E 100(2019) 043303

9. R. Liu, K. Song, Z. Hu, W. Cao, J. Shuai,S. Chen, H. Nan, Y. Zhen, X. Jiang, H. Zhang, W. Han, Y. Liao, J. Qu, Y.Jiao, Jing Fan, L. Liu, "Diversity of collective migration patterns of invasive breast cancer cells emerging during microtrack invasion", Physical Review E 99, 062403 (2019)

10. W. Diao, X. Tong, C. Yang, F. Zhang, C.Bao, C. Hao, L. Liu,M. Li, F. Ye, Q. Fan, J. Wang, Z. Ou-Yang,"Behaviors of glioblastoma cells in in vitro microenvironments", Scientific Reports 9:85(2019)

11. Y. Wu, W. Chen, Z. Wan, A. Djurisic, X.Feng, L. Liu, G. Chen, R. Liu, Z. He, "Multifunctional atomic force probes for Mn2+ doped perovskite solar cells", Journal of Power Sources 425(2019) 130-137 (2019)

12. A. Wu, D. Liao, V. Kirilin, K. Lin, G.Torga, J. Qu, L. Liu, J. Sturm, K. Pienta, R. Austin,"Cancer dormancy and criticality from a game theory      perspective", Cancer Convergence DOI 10.1186/s41236-018-0008-0 (2018)

13. H. Xie, Y. Jiao, Q. Fan, M. Hai, J. Yang,Z. Hu, Y. Yang, J. Shuai, G. Chen, R. Liu, L. Liu,"Modeling three-dimensional invasive solid tumor growth in      heterogeneous microenvironment under chemotherapy", Plos One 13(10): e0206292 (2018)

14. Y. Wu, W. Chen, Y. Lin, B. Tu, Z. Wu, R.Liu, L. Liu, A. Djuri?i?, Z. He, "General Method To Define the Type of Carrier Transport Materials for Perovskite Solar Cells via Kelvin Probes Microscopy", ACS Appl. Energy Mater. 1,3984-3991 (2018)

15. Y. Wu, W. Chen, G. Chen, L. Liu,Z. He, R. Liu, "The Impact of Hybrid Compositional Film/Structure on Organic-Inorganic Perovskite Solar Cells”, Nanomaterials 8(6) doi: 10.3390/nano8060356 (2018)

16. H. Nan, L. Liang, G. Chen, L. Liu,R. Liu, Y. Jiao, "Realizations of highly heterogeneous collagen networks via stochastic reconstruction for micromechanical analysis of tumor cell invasion", Physical Review E 97 (3)033311 (2018)

17. K. Song, Z. Wang, R. Liu, G. Chen, L.Liu, "Microfabrication-Based Three-Dimensional (3-D) Extracellular Matrix Microenvironments for Cancer and Other      Diseases", International Journal of Molecular Science 19(4) doi:10.3390/ijms19040935 (2018)

18. K. Song, Y. Wu, X. Chen, Y. He, L. Liu, G. Chen, R. Liu, "SKPM study on organic-inorganic perovskite materials", AIP Advances 8 (3) 0351114 (2018)

19. Y. Liu, X. Zhang, Y. Wu, W. Liu, X. Li,R. Liu, L. Liu, J. Shuai, "Derivation of persistent time for anisotropic migration of cells", Chin. Phys. B Vol.26, No. 12 (2017) 128707 (2017)

20. Q. Fan, R. Liu, Y. Jiao, C. Tian, James D. Farrell, X. Wang, F. Zhang, W. Yuan, H. Han, J. Chen, Y Yang, X. Zhang, F. Ye, M. Li, Z. Ouyang, and L. Liu, "A novel 3-D bio-microfluidic system mimicking in vivo heterogeneous tumour  microstructure reveals complex tumourstroma interactions", Lab on a Chip DOI:10.1039/C7LC00191F (2017)

21. W. Han, S. Chen, W.Yuan, Q. Fan, J. Tian,X. Wang, L. Chen, X. Zhang, W. Wei, R. Liu, Junle Qu, Y. Jiao, Robert      H.Austin, and L. Liu, "Oriented collagen fibers direct tumor cell intravasation", Proc. Natl. Acad. Sci. USA (2016)

22. R. Liu, Y.Li, and L. Liu, "Single molecule fluorescence spectroscopy for quantitative biological applications", Quantitative Biology 177–191(2016)

23. G. Wang , X. Wang , T. Liu , R. Liu , and L. Liu, "In vitro experimental models and their molding technology of tumor cell", Acta. Phys. Sin. 65,188700      (2016)

24. H. Wang, J. Liu, X. Zheng, X. Rong, X.Zheng, H. Peng, Z. S. Li, M. Li, L. Liu, "Three-dimensional virtual surgery models for percutaneous coronary intervention (PCI) optimization strategies", Sci. Rep. 5,10945 (2015)

25. J. Zhu, L. Liang, Y. Jiao, L. Liu, "Enhanced Invasion of Metastatic Cancer Cells via Extracellular Matrix Interface", PLoS ONE 10,1371 (2015)

26. L. Liu, G.Duclos, B. Sun, J. Lee, A. Wu, Y. Kam, E. D. Sontag, H. A. Stone, J. C. Sturm, R. A. Gatenby and R. H. Austin, "Minimization of thermodynamic      costs in cancer cell invasion", Proc. Natl. Acad. Sci. USA 10.1073 (2013)

27. L. Liu, B.Sun, K. Aw Yong, R. Getzenberg, H. Stone and R. Austin, “Probing the invasiveness of prostate cancer cells in a 3D microfabricated      landscape”, Proc. Natl. Acad. Sci. USA 108:6853–6856 (2011)（高亮文章）

28. L. Liu, K.Loutherback, D. Liao, D. Yeater, G. Lambert, A. Estevez-Torres, J. Sturm, R. Getzenberg and R. Austin, “A microfluidic device for continuous cancer cell culture and passage with hydrodynamic forces”, Lab on a Chip 10, 1807-1813 (2010)

29. L. Liu, W.Cao, J. Wu, W. Wen, D. C. Chang and P. Sheng, “Design and Integration of an All-in-One Biomicrofluidic Chip”, Biomicrofluidics 2,034103(2008)

30. L. Liu, S.Peng, W. Wen and P. Sheng, “Micro Thermo Indicators and Optical-Electronic Temperature Control for Microfluidic Applications”, Appl. Phys.Lett.91, 093513 (2007)

31. L. Liu, S.Peng, W. Wen and P. Sheng, “ Paperlike thermochromic display”, Appl.Phys. Lett. 90 213508 (2007)

32. L. Liu, S.Peng, X. Niu and W. Wen, “Microheater fabricated from a conducting composite”, Appl. Phys. Lett. 89, 223521 (2006)

33. L. Liu, X. Niu, W. Wen and P. Sheng, “Electrorheological fluid-actuated flexible platform”, Appl. Phys. Lett. 88, 173505 (2006)

34. L. Liu, X.Chen, X. Niu, W. Wen, and P. Sheng, “Electrorheological fluid actuated microfluidic pump”, Appl. Phys. Lett. 89, 083505 (2006)

35. L. Liu, X.Huang, C. Shen, Z. Liu, J. Shi, W. Wen and P. Sheng, “Parallel-field electrorheological clutch: Enhanced high shear rate performance”, Appl.      Phys. Lett. 87, 104106 (2005)